Delivering
High-Quality Data.
On-time.
On-budget.
Micro- and Macro-metastasis
Initial survival of cancer cell disseminated from primary tumor may yield either a dormant micrometastasis or…Elimination of Cancer Cells by Specific T-Cells
In Vitro (human and mouse cells): 1. Mixed Lymphocyte Reaction Assay (MLR). 2. …T-Cell Proliferation
In Vitro (human and mouse cells): 1. Mixed Lymphocyte Reaction Assay (MLR). 2. T-Cell proliferation. 3. Maturation of…Tumor Antigen
In Vitro (human and mouse cells): 1. Mixed Lymphocyte Reaction Assay (MLR). 2. T-Cell proliferation. 3. Maturation of…Drug Sensitivity
Many of our clients want deeper insight into the in vitro growth of their selected tumor system. The interplay…Cell Death and Proliferation
Many of our clients want deeper insight into the in vitro growth of their selected…Circulating Tumor Cells
We detect, analyze and isolate circulating tumor cells from mouse models and patient…Invasion and Migration
BioTest4U has experience with specialized assays analyzing the single-migration (SSM)…Primary Tumor Growth
We can implant any cancer cell line available for licensing into mammary fat pad, lungs…Mission
BioTest4U staff has experience with simple and complex analyses of metastatic progression, as well as of primary tumor growth and anti-tumor immunity. These services are devoted to our customers from Biotech/Pharma companies, but also to Food Industry customers that are interested in testing cancer prevention and intervention potential of their additives or dietary supplements.
BioTest4U offers research services for determining efficacy of experimental anti-cancer compounds in models of primary and metastatic tumors. We also provide solutions for pharmacokinetics and phamacodynamics studies.
Metastatic progression is a series of usually low efficacy steps. It starts with the invasion of primary tumor cells into the vicinity of blood or lymphatic vessels. Next, cancer cells enter circulation and get trapped in narrow capillaries in the target organ as dormant micrometastases. In the final step, these micrometastases eventually form actively growing macrometastases that kill patients. Anti-metastatic activity of a prospective drug targeting any of these steps, or activating anti-tumor immunity, has a potential to bring clinical benefit.
Core Tumor Models Services
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Orthotopic and ectopic metastatic progression and primary tumor growth models. Diverse solid and hematologic tumor models available.
Auxiliary Services
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Protein and standard metabolism markers.
Services
About
Samuel Godar, PhD
President
Samuel Godar is founder and President of BioTest4U, Inc. He obtained PhD from Immunology/Biochemistry at the University of Vienna in Austria. He did his postdoctoral research at the Whitehead Institute for Biomedical Research / MIT, Cambridge, MA. Dr. Godar then became Assistant Professor at the Department of Cancer Biology, College of Medicine, University of Cincinnati, Cincinnati, OH.
In 2013 he founded contract research company Biotest4U, which provides services and support for development of oncology drugs.
